Functional Receptors in the Avian Kidney for C-Type Natriuretic Peptide

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Functional Receptors in the Avian Kidney for C-Type Natriuretic Peptide.

Renal actions of avian-specific C-type natriuretic peptide (chCNP) were investigated in the conscious Pekin duck. Under conditions of steady-state renal water and salt elimination, systemic chCNP administration (6 and 30 pmol/min x kg BW for 20 min) dose dependently induced transient natriuresis and diuresis. Mean arterial pressure and heart rate remained constant throughout the experiment. Emp...

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C-type natriuretic peptide upregulates vascular endothelin type B receptors.

Cultured rat vascular smooth muscle cells (VSMCs) possess receptors for potent vasoconstrictor endothelin-1 (ET-1) as well as potent vasodilator natriuretic peptides (atrial, brain, and C-type natriuretic peptides [ANP, BNP, and CNP, respectively]). However, little is known about molecular interactions between endothelin receptors and natriuretic peptides in VSMCs. To elucidate whether natriure...

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Urinary C-Type Natriuretic Peptide

Cardiorenal Research La , Rochester, Minnesota; a innesota. This work was O1 HL36634 and PO1 H tional Research (grant no lingham, Ms. Heublein, D the use of urinary C-type hey have no relationships pt received November 13 cepted December 5, 2012 his study was conducted to determine whether urinary excretion of C-type natriuretic peptide (CNP) is elevated in acute decompensated heart failure (AD...

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C-type natriuretic peptide enhances amylase release through NPR-C receptors in the exocrine pancreas.

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N-terminal pro-C-type natriuretic peptide, but not C-type natriuretic peptide, is greatly elevated in the fetal circulation.

We have identified recently a new peptide, NT-proCNP(1-50) (N-terminal pro-C-type natriuretic peptide), in the circulation of humans and sheep. A previous report of an elevated fetal-maternal gradient in immunoreactive CNP raised the possibility that processing and metabolism of proCNP may differ in maternal and fetal tissues. We therefore collected matching peripheral maternal and umbilical co...

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ژورنال

عنوان ژورنال: Endocrinology

سال: 1999

ISSN: 0013-7227

DOI: 10.1210/en.140.4.1622